Edison Scientific

BixBench3: Research-Study-Scale Computational Biology

Twenty research-study-scale computational biology tasks with 138 programmatically graded artifacts.

computational-biologybioinformaticscodetabular
Status
curated
Saturation
unknown
Reproduction
not yet
Published results
19 results

Editor's note

Models implement study-scale analysis plans and produce artifacts graded against published references. The displayed metric is mean artifact score, not fully reproduced studies. The public runner uses Inspect; dataset access requires separate approval.

Published results

20-task cohort · artifact grading

Mean artifact score across 20 research-study tasks (138 graded artifacts), not the percentage of entirely reproduced studies. The source's fallback configuration remains separately labeled. Valid-answer rates and confidence intervals are not reported here.

ModelScoreVariantSource
claude-fable-5.1 (with fallback)51.5% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
claude-fable-5.1 (with fallback) / — / max
2026-09-21
claude-opus-5.550.2% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
claude-opus-5.5 / — / max
2026-09-26
gpt-6-astra49.2% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
gpt-6-astra / — / max
2026-09-07
grok-4.648.8% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
grok-4.6 / — / max
2026-09-09
gpt-5.6-sol48.0% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
gpt-5.6-sol / — / max
2026-08-26
kimi-k347.0% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
kimi-k3 / — / max
2026-08-26
gpt-6-sol47.0% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
gpt-6-sol / — / max
2026-09-26
glm-5.246.3% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
glm-5.2 / — / max
2026-08-26
claude-opus-4.846.0% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
claude-opus-4.8 / — / max
2026-08-26
gpt-5.543.1% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
gpt-5.5 / — / max
2026-08-26
gemini-3.5-flash42.1% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
gemini-3.5-flash / — / max
2026-08-26
claude-opus-540.6% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
claude-opus-5 / — / max
2026-08-26
gpt-6-luna36.9% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
gpt-6-luna / — / max
2026-09-26
gpt-5.4-mini36.4% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
gpt-5.4-mini / — / max
2026-08-26
gpt-5.4-nano27.5% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
gpt-5.4-nano / — / max
2026-08-26
gemini-3.1-pro-preview24.8% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
gemini-3.1-pro-preview / — / max
2026-08-26
claude-sonnet-4.615.3% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
claude-sonnet-4.6 / — / max
2026-08-26
claude-haiku-4.51.5% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
claude-haiku-4.5 / — / max
2026-08-26
gemini-3.1-flash-lite0.0% mean artifact scoreBase · max · 20 studies / 138 artifactsEdison Scientific · BixBench3 · overall
gemini-3.1-flash-lite / — / max
2026-08-26

Sources

  • external Edison Scientific · BixBench3 · overall
  • external Official runner and grading implementation
  • paper benchmark paper